Research > Focus A > Work Packages A03
Summary
In this project, preclinical models and NCT Neuro MASTER Match (N2M2) study cohort-derived tissues of patients with newly diagnosed and recurrent glioblastoma will be used to decipher molecular, cellular and imaging determinants of response and resistance to precision treatments in glioblastoma. With this research, patient groups likely to benefit from a molecularly targeted intervention will be characterized, predictive biomarkers selected and prioritized, and parallel as well as subsequent treatments will be developed to enhance therapeutic benefit in selected molecularly defined subgroups. The visual abstract below shows the aims and planned tasks of the work package.