Research > Focus C
Prof. Dr. med. Stefan M. Pfister
Hopp-Children´s Comprehensive Cancer Center at the NCT Heidelberg, Division of Pediatric Neurooncology, DKFZ Heidelberg
The work packages of Focus C in conjunction with the molecular information of Focus A will provide and expand a diagnostic platform, which is capable of coping with the needs of trialists and clinicians for assessment of heterogeneity, real-time non-invasive assessment of response and resistance and the generation of signatures or footprints allowing for personalized treatments. Further, Focus C will provide central data on a drug and biological repository as well as on different radiation qualities (together with B05) to be used not only in the other work packages but also in further clinical studies. Specific advanced outcomes may be automated glioblastoma MRI diagnostics and integration of metabolic signatures from globally available tissue resources without the need for demanding freezing processes and the potential for developing phase 0 trials.
Link to: C01: Comprehensive preclinical pharmacology testing of drugs used for glioblastoma treatment in children and adults
C01
Comprehensive Preclinical Pharmacology Testing of drugs used for glioblastoma treatment in children and Adults
Prof. Dr. med. Walter E. Haefeli
University Hospital of Heidelberg, Department of Clinical Pharmacology and Pharmacoepidemiology
Link to: C02: Radiomics, radiogenomics and deep-learning in neurooncology
C02
Radiomics, Radiogenomics and Deep-Learning in Neuro-Oncology
Prof. Dr. med. Martin Bendszus
University Hospital Heidelberg, Department of Neuroradiology
Dr. med. Philipp Kickingereder
University Hospital Heidelberg, Department of Neuroradiology
Link to: C03: Imaging immune signatures of glioma response and resistance towards immunotherapy
C03
Imaging IMMUNE signatures of glioma Response and resistance towards immunotherapy
Dr. med. Michael Breckwoldt
PhD, University Hospital Heidelberg, Department of Neuroradiology
Link to: C04: Identification and spatial mapping of metabolic resistance factors by MALDI mass spectrometry imaging
C04
Identification and spatial mapping of metabolic resistance factors by MALDI mass spectrometry imaging
Prof. Dr. rer. nat. Carsten Hopf
Hochschule Mannheim, Center for Mass Spectrometry and Optical Spectroscopy
Dr. med. Christiane A. Opitz
German Cancer Research Center (DKFZ), Brain Cancer Metabolism Group
Link to: C05: Overcoming glioma radio-resistance with particle therapy
C05
Overcoming glioma radio-resistance with particle therapy
Dr. med. Dr. rer. nat. Amir Abdollahi
University Hospital Heidelberg, Radiationoncology, UKHD
Dr. rer. nat. Ivana Dokic
University Hospital Heidelberg, Radiationoncology, UKHD