UNITE Glioblastoma
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    • Participating Institutions
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      • Spokesperson and Co-Spokespersons
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  • Research
    • Focus A
      • A01: Targeting tumor cell network communication to overcome primary and adaptive resistance in glioblastoma
      • A02: Development of a specific combination therapy for histone H3-mutant pediatric glioblastoma
      • A03: Deciphering resistance against targeted treatments
      • A04: Elucidating tumor-associated microglia interactions in astrocytomas CNS WHO-grade 4
      • A05: Predictive biomarkers for MGMT-promoter-methylated glioblastoma (2019 – 2023)
      • A06: Resistance mechanisms of glioblastoma against alkylating agents and radiotherapy
      • A07: Mapping and targeting neuron-tumor networks to tackle therapy resistance in glioblastoma
      • A08: Personalized glioblastoma treatment guided by patient-derived tumor organoids
    • Focus B
      • B01: Mechanisms of response and resistance to glioma-specific t cells
      • B02: DNA mis-match repair regulates immune checkpoint blockade therapy in glioblastoma (2019 – 2023)
      • B03: Targeting immunosuppressive programs in isocitrate dehydrogenase mutant gliomas
      • B04: Impact of myeloid cells on the adaptive immune response in newly diagnosed and recurrent glioblastomas
      • B05: Dissecting the response of glioblastoma and its tumor microenvironment to focused high-dose radiotherapy (2019 – 2023)
      • B06: Visualization and characterization of immune responses in H3K27M mutant gliomas
      • B07A: Targeting the post-radiogenic tumor microenvironment
    • Focus C
      • C01: Comprehensive preclinical pharmacology testing of drugs used for glioblastoma treatment
      • C02: Radiomics, radiogenomics and deep-learning in neurooncology
      • C03: Imaging immune signatures of glioma response and resistance towards immunotherapy (2019 – 2023)
      • C04: Metabolic signaling in glioblastoma: a spatial multi-omics approach
      • C05: Overcoming glioma radio-resistance with particle therapy
      • C06: Functional characterization of EGFR structural variants associated with long-term survival in glioblastoma, IDH-WT
    • Focus D
      • D01: Integrated tissue core
      • D02: Data integration, bioinformatics analysis, and data exploration for precision neurooncology
      • D03: Integrated research training group – UNITE School of Neurooncology
      • UNITE Core Collection
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Im Neuenheimer Feld 400
69120 Heidelberg

Themen

  • About
  • Research
  • Members
  • Events
  • School
  • News
  • Contact

Research

  • Focus A
    • A01: Targeting tumor cell network communication to overcome primary and adaptive resistance in glioblastoma
    • A02: Development of a specific combination therapy for histone H3-mutant pediatric glioblastoma
    • A03: Deciphering resistance against targeted treatments
    • A04: Elucidating tumor-associated microglia interactions in astrocytomas CNS WHO-grade 4
    • A05: Predictive biomarkers for MGMT-promoter-methylated glioblastoma (2019 – 2023)
    • A06: Resistance mechanisms of glioblastoma against alkylating agents and radiotherapy
    • A07: Mapping and targeting neuron-tumor networks to tackle therapy resistance in glioblastoma
    • A08: Personalized glioblastoma treatment guided by patient-derived tumor organoids

Research

  • Focus B
    • B01: Mechanisms of response and resistance to glioma-specific t cells
    • B02: DNA mis-match repair regulates immune checkpoint blockade therapy in glioblastoma (2019 – 2023)
    • B03: Targeting immunosuppressive programs in isocitrate dehydrogenase mutant gliomas
    • B04: Impact of myeloid cells on the adaptive immune response in newly diagnosed and recurrent glioblastomas
    • B05: Dissecting the response of glioblastoma and its tumor microenvironment to focused high-dose radiotherapy (2019 – 2023)
    • B06: Visualization and characterization of immune responses in H3K27M mutant gliomas

Research

  • Focus C
    • C01: Comprehensive preclinical pharmacology testing of drugs used for glioblastoma treatment
    • C02: Radiomics, radiogenomics and deep-learning in neurooncology
    • C03: Imaging immune signatures of glioma response and resistance towards immunotherapy (2019 – 2023)
    • C04: Metabolic signaling in glioblastoma: a spatial multi-omics approach
    • C05: Overcoming glioma radio-resistance with particle therapy
    • C06: Functional characterization of EGFR structural variants associated with long-term survival in glioblastoma, IDH-WT

Research

  • Focus D
    • D01: Integrated tissue core
    • D02: Data integration, bioinformatics analysis, and data exploration for precision neurooncology
    • D03: Integrated research training group – UNITE School of Neurooncology
    • UNITE Core Collection
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